Genome Diversity Center
at the Institute of Evolution, University of Haifa
(Since August 2000)
Head: Edward N. Trifonov
Is fast adaptation there, in the sequences?
The highly diverse phenotypical features could be matched only by highly
diverse component of the genome - tandemly repeating sequences.
The copy numbers of the repeats seem to act as tuners of the gene expression
and higher phenotypical levels.
Trifonov, E. N., The tuning function of the tandemly repeating sequences: molecular device for fast adaptation.
In: Evolutionary Theory and Processes: Modern Horizons, Wasser, S. P. (Ed.),
Kluwer Academic Publishers, pp 115-138 (2004)
Trifonov, E. N., Tandem repeats.
In: "Encyclopedia of Molecular Biology", T. E. Creighton, Ed., John Wiley & Sons, Inc.,
New York, 1999, p. 2513-2514
Trifonov, E. N., Elucidating sequence codes: three codes for evolution.
Annals NY Acad. Sci. 870, 330-338 (1999).
(Title of the volume: Molecular Strategies in Biological Evolution, Ed. L. Caporale).
Trifonov, E. N., Making sense of the human genome.
In: "Structure and Methods, vol. 1, Human Genome Initiative and DNA Recombination",
(Eds. R. H. Sarma and M. H. Sarma), Adenine Press, New York, 1990, pp. 69-77
Trifonov, E. N., The multiple codes of nucleotide sequences.
Bull. Math. Biol. 51, 417-432 (1989)