Genome Diversity Center

at the Institute of Evolution, University of Haifa

(Since August 2000)
Head: Edward N. Trifonov




What is gained by superposition of the codes?


The superposition of the codes brings about sequence economy and enhances survivability.

Relevant references:


Peleg, O., Kirzhner, V. M., Trifonov, E. N., Bolshoy, A., Overlapping messages and survivability. J. Molec. Evol. 59, 520-527 (2004).

Peleg, O., Trifonov, E. N., Bolshoy, A.,
Hidden messages in the nef gene of human immunodeficiency virus Type 1 suggest a novel RNA secondary structure.
Nucl. Acids Res. 31, 4192-4200 (2003)

Peleg, O., Brunak, S., Trifonov, E. N., Nevo, E., and Bolshoy, A.,
RNA secondary structure and sequence conservation in C1 region of human immunodeficiency virus type 1 env gene,
AIDs Res. and Human Retroviruses 18, 867-878 (2002)

Denisov, D. A., Shpigelman, E. S., Trifonov, E. N.,
Protective nucleosome centering at splice sites as suggested by sequence-directed mapping of the nucleosomes.
Gene 205, 145-149 (1997)

Trifonov, E. N., Genetic sequences as product of compression by inclusive superposition of many codes.
Molecular Biology 31, 759-767 (1997)

Trifonov, E. N., Gene splicing: spatial separation of overlapping messages.
Computers Chem. 17, 27-31 (1993)

Trifonov, E. N., The multiple codes of nucleotide sequences.
Bull. Math. Biol. 51, 417-432 (1989)